Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional dissection of adenylate cyclase R, an inducer of spore encapsulation.

The Journal of biological chemistry - 31 Dec 2010

Chen Zhi-hui, Schilde Christina, Schaap Pauline

Abstract excerpt

Cyclic AMP acting on protein kinase A controls sporulation and encystation in social and solitary amoebas. In Dictyostelium discoideum, adenylate cyclase R (ACR), is essential for spore encapsulation. In addition to its cyclase (AC) domain, ACR harbors seven transmembrane helices, a histidine kinase domain, and two receiver domains. We investigated the role of these domains in the regulation of AC activity....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenylyl Cyclases
Share to Dictyostelium
Share to Dimerization

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Histidine Kinase

Share to Luminescent Proteins

Share to Microscopy, Fluorescence

Share to Protein Kinases

Share to Spores

Source

Open in PubMed Open full text

Identifiers

PMID: 20966074
DOI: 10.1074/jbc.M110.156380
PMCID: PMC3009899

Genes

ACR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional dissection of adenylate cyclase R, an inducer of spore encapsulation.PMID 20966074Read ↗

An adenylyl cyclase that functions during late development of Dictyostelium.Semantic proximity Read ↗

A conserved signalling pathway for amoebozoan encystation that was co-opted for multicellular development.Semantic proximity Read ↗

Activated cAMP receptors switch encystation into sporulation.Semantic proximity Read ↗

cAMP production by adenylyl cyclase G induces prespore differentiation in Dictyostelium slugs.Semantic proximity Read ↗

Constitutively active adenylyl cyclase mutant requires neither G proteins nor cytosolic regulators.Semantic proximity Read ↗

Regulation of adenylyl cyclases by a region outside the minimally functional cytoplasmic domains.Semantic proximity Read ↗

Multiple developmental roles for CRAC, a cytosolic regulator of adenylyl cyclase.Semantic proximity Read ↗

Ege A, a novel C2 domain containing protein, is essential for GPCR-mediated gene expression in dictyostelium.Semantic proximity Read ↗

A temperature-sensitive adenylyl cyclase mutant of Dictyostelium.Semantic proximity Read ↗

LagC is required for cell-cell interactions that are essential for cell-type differentiation in Dictyostelium.Semantic proximity Read ↗

A novel adenylyl cyclase detected in rapidly developing mutants of Dictyostelium.Semantic proximity Read ↗

Isolation of inactive and G protein-resistant adenylyl cyclase mutants using random mutagenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.