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Article

Ege A, a novel C2 domain containing protein, is essential for GPCR-mediated gene expression in dictyostelium.

Developmental biology - 1 Aug 2002

Zhang Ning, Long Yu, Devreotes Peter N

Abstract excerpt

During early stages of development, expression of aggregative genes in Dictyostelium is regulated by G protein-linked signaling pathways. We have isolated an aggregation-deficient mutant from a restriction enzyme-mediated insertional mutagenesis screen and have obtained its cDNA. Since the mutant expresses prestarvation genes but fails to express early genes, such as cAR1 and GP80, during development, we...

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PMID: 12142016
DOI: 10.1006/dbio.2002.0715

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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