Article
An intersection of the cAMP/PKA and two-component signal transduction systems in Dictyostelium.
The EMBO journal - 15 May 1998
Thomason P A, Traynor D, Cavet G, Chang W T, Harwood A J, Kay R R
Abstract excerpt
Terminal differentiation of both stalk and spore cells in Dictyostelium can be triggered by activation of cAMP-dependent protein kinase (PKA). A screen for mutants where stalk and spore cells mature in isolation produced three genes which may act as negative regulators of PKA: rdeC (encoding the...
Topics
- 3',5'-Cyclic-AMP Phosphodiesterases
- Animals
- Base Sequence
- Binding Sites
- Cyclic AMP-Dependent Protein Kinases
- DNA, Fungal
- Dictyostelium
- Enzyme Activation
- Molecular Sequence Data
- Mutation
- Phosphates
- Phosphorylation
- Protozoan Proteins
- Signal Transduction
- Spores, Fungal