Article
A role for cAMP-dependent protein kinase A in early Dictyostelium development.
Genes & development - 1 Jan 1990
Firtel R A, Chapman A L
Abstract excerpt
In Dictyostelium, cAMP functions as an extracellular regulatory molecule that controls aggregation, expression of a number of classes of genes, and cellular differentiation by binding to cell-surface receptors that activate intracellular signal transduction pathways. To investigate possible roles for intracellular cAMP, we have overexpressed the wild-type mouse type-I regulatory subunit (RI) of cAMP-dependent...
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