Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An adenylyl cyclase that functions during late development of Dictyostelium.

Development (Cambridge, England) - 1 Dec 1999

Söderbom F, Anjard C, Iranfar N, Fuller D, Loomis W F

Abstract excerpt

A variety of extracellular signals lead to the accumulation of cAMP which can act as a second message within cells by activating protein kinase A (PKA). Expression of many of the essential developmental genes in Dictyostelium discoideum are known to depend on PKA activity. Cells in which the receptor-coupled adenylyl cyclase gene, acaA, is genetically inactivated grow well but are unable to develop. Surprisingly,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenylyl Cyclases
Share to Dictyostelium
Share to Gene Expression Regulation, Developmental

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Histidine Kinase

Share to Molecular Chaperones

Share to Mutagenesis

Share to Protein Kinases

Share to Protozoan Proteins

Source

Identifiers

PMID: 10556070
DOI: 10.1242/dev.126.23.5463

Genes

ACR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An adenylyl cyclase that functions during late development of Dictyostelium.PMID 10556070Read ↗

A temperature-sensitive adenylyl cyclase mutant of Dictyostelium.Semantic proximity Read ↗

amiB, a novel gene required for the growth/differentiation transition in Dictyostelium.Semantic proximity Read ↗

A conserved signalling pathway for amoebozoan encystation that was co-opted for multicellular development.Semantic proximity Read ↗

Functional dissection of adenylate cyclase R, an inducer of spore encapsulation.Semantic proximity Read ↗

A novel adenylyl cyclase detected in rapidly developing mutants of Dictyostelium.Semantic proximity Read ↗

A novel Myb homolog initiates Dictyostelium development by induction of adenylyl cyclase expression.Semantic proximity Read ↗

Multiple developmental roles for CRAC, a cytosolic regulator of adenylyl cyclase.Semantic proximity Read ↗

Genome-wide expression analyses of gene regulation during early development of Dictyostelium discoideum.Semantic proximity Read ↗

Constitutively active adenylyl cyclase mutant requires neither G proteins nor cytosolic regulators.Semantic proximity Read ↗

Regulation of Dictyostelium early development genes in signal transduction mutants.Semantic proximity Read ↗

A role for cAMP-dependent protein kinase A in early Dictyostelium development.Semantic proximity Read ↗

An immediate-early gene, srsA: its involvement in the starvation response that initiates differentiation of Dictyostelium cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.