Article
Expression and properties of wild-type and mutant forms of the Drosophila sex comb on midleg (SCM) repressor protein.
Genetics - 1 Oct 1998
Bornemann D, Miller E, Simon J
Abstract excerpt
The Sex comb on midleg (Scm) gene encodes a transcriptional repressor of the Polycomb group (PcG). Here we show that SCM protein is nuclear and that its expression is widespread during fly development. SCM protein contains a C-terminal domain, termed the SPM domain, which mediates protein-protein...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Antibodies
- Cell Nucleus
- Chromosomes
- DNA Mutational Analysis
- DNA-Binding Proteins
- Drosophila Proteins
- Drosophila melanogaster
- Female
- Gene Expression
- Genes, Insect
- Genes, Lethal
- Insect Proteins
- Male
- Molecular Sequence Data
- Mutation