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Article

Persistent replicative stress alters polycomb phenotypes and tissue homeostasis in Drosophila melanogaster.

Cell reports - 8 May 2014

Landais Severine, D'Alterio Cecilia, Jones D Leanne

Abstract excerpt

Polycomb group (PcG) proteins establish and maintain genetic programs that regulate cell-fate decisions. Drosophila multi sex combs (mxc) was categorized as a PcG gene based on a classical Polycomb phenotype and genetic interactions; however, a mechanistic connection between Polycomb and Mxc has not been elucidated. Hypomorphic alleles of mxc are characterized by male and female sterility and ectopic sex combs....

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Identifiers

PMID: 24746823
DOI: 10.1016/j.celrep.2014.03.042
PMCID: PMC4048808

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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