Article
Requirement for sex comb on midleg protein interactions in Drosophila polycomb group repression.
Genetics - 1 Jul 2004
Peterson Aidan J, Mallin Daniel R, Francis Nicole J, Ketel Carrie S, Stamm Joyce, Voeller Rochus K, Kingston Robert E, Simon Jeffrey A
Abstract excerpt
The Drosophila Sex Comb on Midleg (SCM) protein is a transcriptional repressor of the Polycomb group (PcG). Although genetic studies establish SCM as a crucial PcG member, its molecular role is not known. To investigate how SCM might link to PcG complexes, we analyzed the in vivo role of a conser...
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