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Article

Molecular genetic analysis of Suppressor 2 of zeste identifies key functional domains.

Genetics - 1 Aug 2009

Emmons Richard B, Genetti Heather, Filandrinos Stephen, Lokere Jillian, Wu Chao-ting

Abstract excerpt

The Su(z)2 complex contains Posterior sex combs (Psc) and Suppressor 2 of zeste [Su(z)2], two paralogous genes that likely arose by gene duplication. Psc encodes a Polycomb group protein that functions as a central component of the PRC1 complex, which maintains transcriptional repression of a wide array of genes. Although much is known about Psc, very little is known about Su(z)2, the analysis of which has been...

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Identifiers

PMID: 19528329
DOI: 10.1534/genetics.108.097360
PMCID: PMC2728886

Genes

PRC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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