Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

WAVE/SCAR, a multifunctional complex coordinating different aspects of neuronal connectivity.

Developmental biology - 15 Oct 2004

Schenck Annette, Qurashi Abrar, Carrera Pilar, Bardoni Barbara, Diebold Céline, Schejter Eyal, Mandel Jean-Louis, Giangrande Angela

Abstract excerpt

Although it is well established that the WAVE/SCAR complex transduces Rac1 signaling to trigger Arp2/3-dependent actin nucleation, regulatory mechanisms of this complex and its versatile function in the nervous system are poorly understood. Here we show that the Drosophila proteins SCAR, CYFIP and Kette, orthologs of WAVE/SCAR complex components, all show strong accumulation in axons of the central nervous system...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptor Proteins, Signal Transducing
Share to Cell Movement

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fragile X Mental Retardation Protein

Share to In Situ Hybridization

Share to Macromolecular Substances

Share to Microfilament Proteins

Share to Neuromuscular Junction

Share to RNA-Binding Proteins

Source

Identifiers

PMID: 15385157
DOI: 10.1016/j.ydbio.2004.07.009

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

WAVE/SCAR, a multifunctional complex coordinating different aspects of neuronal connectivity.PMID 15385157Read ↗

CYFIP dependent actin remodeling controls specific aspects of Drosophila eye morphogenesis.Semantic proximity Read ↗

SCAR is a primary regulator of Arp2/3-dependent morphological events in DrosophilaSemantic proximity Read ↗

The WAVE/SCAR complex promotes polarized cell movements and actin enrichment in epithelia during C. elegans embryogenesis.Semantic proximity Read ↗

Drosophila cyfip regulates synaptic development and endocytosis by suppressing filamentous actin assembly.Semantic proximity Read ↗

HSPC300 and its role in neuronal connectivity.Semantic proximity Read ↗

Drosophila Kette coordinates myoblast junction dissolution and the ratio of Scar-to-WASp during myoblast fusion.Semantic proximity Read ↗

Molecular Dissection of Neurodevelopmental Disorder-Causing Mutations in CYFIP2.Semantic proximity Read ↗

CYFIP/Sra-1 controls neuronal connectivity in Drosophila and links the Rac1 GTPase pathway to the fragile X protein.Semantic proximity Read ↗

Molecular dissection of neurodevelopmental disorder-causing mutations in CYFIP2Semantic proximity Read ↗

SCAR/WAVE and Arp2/3 are crucial for cytoskeletal remodeling at the site of myoblast fusion.Semantic proximity Read ↗

DOCK7 regulates WNT signaling and NMJ clustering in normal and DMD muscleSemantic proximity Read ↗

Nap1 regulates Dictyostelium cell motility and adhesion through SCAR-dependent and -independent pathways.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.