Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Loss of RapC causes defects in cytokinesis, cell migration, and multicellular development of Dictyostelium.

Biochemical and biophysical research communications - 23 May 2018

Park Byeonggyu, Kim Hyeseon, Jeon Taeck Joong

Abstract excerpt

The small GTPase Ras proteins are involved in diverse cellular processes. We investigated the functions of RapC, one of 15 Ras subfamily GTPases in Dictyostelium. Loss of RapC resulted in a spread shape of cells; severe defects in cytokinesis leading to multinucleation; decrease of migration speed in chemoattractant-mediated cell migration, likely through increased cell adhesion; and aberrations in multicellular...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Adhesion
Share to Cell Movement
Share to Cell Shape

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cytokinesis

Share to Dictyostelium

Share to Protozoan Proteins

Share to rap1 GTP-Binding Proteins

Share to Sequence Homology, Amino Acid

Source

Identifiers

PMID: 29614268
DOI: 10.1016/j.bbrc.2018.03.223

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Loss of RapC causes defects in cytokinesis, cell migration, and multicellular development of Dictyostelium.PMID 29614268Read ↗

Dictyostelium RasG is required for normal motility and cytokinesis, but not growth.Semantic proximity Read ↗

Regulation of Dictyostelium morphogenesis by RapGAP3.Semantic proximity Read ↗

Rac1 GTPases control filopodia formation, cell motility, endocytosis, cytokinesis and development in Dictyostelium.Semantic proximity Read ↗

Rap1, a mercenary among the Ras-like GTPases.Semantic proximity Read ↗

Nap1 regulates Dictyostelium cell motility and adhesion through SCAR-dependent and -independent pathways.Semantic proximity Read ↗

RacG regulates morphology, phagocytosis, and chemotaxis.Semantic proximity Read ↗

The Rap1 GTPase functions as a regulator of morphogenesis in vivo.Semantic proximity Read ↗

A novel Dictyostelium RasGEF required for chemotaxis and development.Semantic proximity Read ↗

PIP₃-dependent macropinocytosis is incompatible with chemotaxis.Semantic proximity Read ↗

SCAR, a WASP-related protein, isolated as a suppressor of receptor defects in late Dictyostelium development.Semantic proximity Read ↗

Cell motility and SCAR localisation in axenically growing Dictyostelium cells.Semantic proximity Read ↗

The Dictyostelium RasS protein is required for macropinocytosis, phagocytosis and the control of cell movement.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.