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Article

SCAR is a primary regulator of Arp2/3-dependent morphological events in Drosophila

18 Feb 2002

Abstract excerpt

The Arp2/3 complex and its activators, Scar/WAVE and Wiskott-Aldrich Syndrome protein (WASp), promote actin polymerization in vitro and have been proposed to influence cell shape and motility in vivo. We demonstrate that the Drosophila Scar homologue, SCAR, localizes to actin-rich structures and is required for normal cell morphology in multiple cell types throughout development. In particular, SCAR function is...

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PMID: 11854309
DOI: 10.1083/jcb.200109057

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SCAR is a primary regulator of Arp2/3-dependent morphological events in DrosophilaPMID 11854309Read ↗

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Signalling to actin assembly via the WASP (Wiskott-Aldrich syndrome protein)-family proteins and the Arp2/3 complexSemantic proximity Read ↗

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