Article
Costars, a Dictyostelium protein similar to the C-terminal domain of STARS, regulates the actin cytoskeleton and motility.
Journal of cell science - 1 Nov 2010
Pang Te-Ling, Chen Fung-Chi, Weng Yi-Lan, Liao Hsien-Ching, Yi Yung-Hsiang, Ho Chia-Lin, Lin Chi-Hung, Chen Mei-Yu
Abstract excerpt
Through analysis of a chemotaxis mutant obtained from a genetic screen in Dictyostelium discoideum, we have identified a new gene involved in regulating cell migration and have named it costars (cosA). The 82 amino acid Costars protein sequence appears highly conserved among diverse species, and significantly resembles the C-terminal region of the striated muscle activator of Rho signaling (STARS), a mammalian...
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