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Article

Prx1 and Prx2 in skeletogenesis: roles in the craniofacial region, inner ear and limbs.

Development (Cambridge, England) - 1 Oct 1998

ten Berge D, Brouwer A, Korving J, Martin J F, Meijlink F

Abstract excerpt

Prx1 and Prx2 are closely related paired-class homeobox genes that are expressed in very similar patterns predominantly in mesenchyme. Prx1 loss-of-function mutants show skeletal defects in skull, limbs and vertebral column (Martin, J. F., Bradley, A. and Olson, E. N. (1995) Genes Dev. 9, 1237-1249). We report here that mice in which Prx2 is inactivated by a lacZ insertion had no skeletal defects, whereas...

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PMID: 9729491
DOI: 10.1242/dev.125.19.3831

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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