Article
The concerted action of Meox homeobox genes is required upstream of genetic pathways essential for the formation, patterning and differentiation of somites.
Development (Cambridge, England) - 1 Oct 2003
Mankoo Baljinder S, Skuntz Susan, Harrigan Ian, Grigorieva Elena, Candia Al, Wright Christopher V E, Arnheiter Heinz, Pachnis Vassilis
Abstract excerpt
The paraxial mesoderm of the somites of the vertebrate embryo contains the precursors of the axial skeleton, skeletal muscles and dermis. The Meox1 and Meox2 homeobox genes are expressed in the somites and their derivatives during embryogenesis. Mice homozygous for a null mutation in Meox1 displa...
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