prx-1 functions cooperatively with another paired-related homeobox gene, prx-2, to maintain cell fates within the craniofacial mesenchyme.

doi:10.1242/dev.126.3.495

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Article

prx-1 functions cooperatively with another paired-related homeobox gene, prx-2, to maintain cell fates within the craniofacial mesenchyme.

Development (Cambridge, England) - 1 Feb 1999

Lu M F, Cheng H T, Kern M J, Potter S S, Tran B, Diekwisch T G, Martin J F

Abstract excerpt

The paired-related homeobox gene, prx-1, is expressed in the postmigratory cranial mesenchyme of all facial prominences and is required for the formation of proximal first arch derivatives. We introduced lacZ into the prx-1 locus to study the developmental fate of cells destined to express prx-1...

Topics

Alleles
Animals
Facial Bones
Genes, Homeobox
Genotype
Homeodomain Proteins
Lac Operon
Mesoderm
Mice
Mice, Transgenic
Mutagenesis
Skull

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