Article
Genetic and molecular control of osterix in skeletal formation.
Journal of cellular biochemistry - 1 May 2013
Sinha Krishna M, Zhou Xin
Abstract excerpt
Osteoblast differentiation is a multi-step process where mesenchymal cells differentiate into osteoblast lineage cells including osteocytes. Osterix (Osx) is an osteoblast-specific transcription factor which activates a repertoire of genes during differentiation of preosteoblasts into mature osteoblasts and osteocytes. The essential role of Osx in the genetic program of bone formation and in bone homeostasis is...
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