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Article

Spatio-temporal dynamics of gene expression of the Edn1-Dlx5/6 pathway during development of the lower jaw.

Genesis (New York, N.Y. : 2000) - 1 Jun 2010

Vieux-Rochas Maxence, Mantero Stefano, Heude Eglantine, Barbieri Ottavia, Astigiano Simonetta, Couly Gérard, Kurihara Hiroki, Levi Giovanni, Merlo Giorgio R

Abstract excerpt

The morphogenesis of the vertebrate skull results from highly dynamic integrated processes involving the exchange of signals between the ectoderm, the endoderm, and cephalic neural crest cells (CNCCs). Before migration CNCCs are not committed to form any specific skull element, molecular signals exchanged in restricted regions of tissue interaction are crucial in providing positional identity to the CNCCs...

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PMID: 20333701
DOI: 10.1002/dvg.20625

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