Article
Requirement for Pbx1 in skeletal patterning and programming chondrocyte proliferation and differentiation.
Development (Cambridge, England) - 1 Sept 2001
Selleri L, Depew M J, Jacobs Y, Chanda S K, Tsang K Y, Cheah K S, Rubenstein J L, O'Gorman S, Cleary M L
Abstract excerpt
Pbx1 and a subset of homeodomain proteins collaboratively bind DNA as higher-order molecular complexes with unknown consequences for mammalian development. Pbx1 contributions were investigated through characterization of Pbx1-deficient mice. Pbx1 mutants died at embryonic day 15/16 with severe hy...
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