Article
Nucleotide-dependent prereplicative complex assembly by Cdc6p, a homolog of eukaryotic and prokaryotic clamp-loaders.
Molecular cell - 1 Jul 1998
Perkins G, Diffley J F
Abstract excerpt
Expression of the Cdc6 protein (Cdc6p) is essential for formation of prereplicative complexes at budding yeast replication origins. Analysis of mutations in the conserved nucleoside triphosphate (NTP)-binding site of Cdc6p described here suggests that NTPs are required both for the productive int...
Topics
- Alleles
- Amino Acid Sequence
- Binding Sites
- Cell Cycle Proteins
- Cloning, Molecular
- DNA Footprinting
- DNA Replication
- DNA, Fungal
- DNA-Binding Proteins
- Fungal Proteins
- Genes, Dominant
- Homeodomain Proteins
- Macromolecular Substances
- Minor Histocompatibility Antigens
- Molecular Sequence Data
- Multigene Family
- Nucleotides
- Proto-Oncogene Proteins c-bcl-2