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Article

Mutational analysis of conserved sequence motifs in the budding yeast Cdc6 protein.

Journal of molecular biology - 11 May 2001

Schepers A, Diffley J F

Abstract excerpt

The Cdc6 protein is required to load a complex of Mcm2-7 family members (the MCM complex) into prereplicative complexes at budding yeast origins of DNA replication. Cdc6p is a member of the AAA(+) superfamily of proteins, which includes the prokaryotic and eukaryotic clamp loading proteins. These proteins share a number of conserved regions of homology and a common three-dimensional architecture. Two of the...

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PMID: 11350163
DOI: 10.1006/jmbi.2001.4637

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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