Article
The Cdc6p nucleotide-binding motif is required for loading mcm proteins onto chromatin.
Proceedings of the National Academy of Sciences of the United States of America - 19 Jan 1999
Weinreich M, Liang C, Stillman B
Abstract excerpt
Cdc6p has an essential function in the mechanism and regulation of the initiation of DNA replication. Budding yeast Cdc6p binds to chromatin near autonomously replicating sequence elements in late M to early G1 phase through an interaction with Origin Recognition Complex or another origin-associa...
Topics
- Adenosine Triphosphate
- Binding Sites
- Cell Cycle
- Cell Cycle Proteins
- Chromatin
- DNA-Binding Proteins
- Flow Cytometry
- Minichromosome Maintenance 1 Protein
- Mitosis
- Mutation
- Origin Recognition Complex
- Protein Binding
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Sequence Homology, Amino Acid
- Transcription Factors