Article
Mapping of polyomavirus middle T domain that is responsible for AP-1 activation.
Oncogene - 11 Jun 1998
Oliveira M L, Roberts T M, Druker B J, Armelin M C
Abstract excerpt
Cell transformation by Polyomavirus middle T (MT) oncoprotein involves binding and activation of several cytoplasmic proteins that participate in growth factors-induced mitogenic signal transduction to the nucleus. We have previously reported that the AP-1 transcriptional complex is a target for MT during cell transformation. To analyse the interactions between MT and cellular proteins that are required for...
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