Mapping of polyomavirus middle T domain that is responsible for AP-1 activation.

doi:10.1038/sj.onc.1201841

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Article

Mapping of polyomavirus middle T domain that is responsible for AP-1 activation.

Oncogene - 11 Jun 1998

Oliveira M L, Roberts T M, Druker B J, Armelin M C

Abstract excerpt

Cell transformation by Polyomavirus middle T (MT) oncoprotein involves binding and activation of several cytoplasmic proteins that participate in growth factors-induced mitogenic signal transduction to the nucleus. We have previously reported that the AP-1 transcriptional complex is a target for...

Topics

3T3 Cells
Androstadienes
Animals
Antigens, Polyomavirus Transforming
Binding Sites
Cell Transformation, Viral
Chromosome Mapping
Enzyme Inhibitors
Gene Expression
Mice
Mutagenesis
Phenotype
Phosphatidylinositol 3-Kinases
Proto-Oncogene Proteins c-jun
Transcription Factor AP-1
Wortmannin

Source

Open in PubMed

Identifiers

PMID: 9662329
DOI: 10.1038/sj.onc.1201841

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9662329-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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