Polyomavirus-induced malignant transformation: comparative analysis of wild type and mutant middle T-overexpressing cell lines.

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Article

Polyomavirus-induced malignant transformation: comparative analysis of wild type and mutant middle T-overexpressing cell lines.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Sept 1996

Armelin M C, Oliveira M L

Abstract excerpt

Polyomavirus, a DNA tumor virus, expresses three viral oncoproteins (large, middle and small T antigens), causes malignant transformation in cell culture and induces multiple tumors in vivo. The middle T (MT) antigen seems to play an essential role in transformation and tumorigenicity. The observ...

Topics

Antigens, Viral, Tumor
Cell Line
Cell Transformation, Viral
Gene Expression Regulation, Viral
Humans
Mutation
Platelet-Derived Growth Factor
Polyomavirus

Source

Open in PubMed

Identifiers

PMID: 9181056

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9181056-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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