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Article

Polyomavirus-induced malignant transformation: comparative analysis of wild type and mutant middle T-overexpressing cell lines.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Sept 1996

Armelin M C, Oliveira M L

Abstract excerpt

Polyomavirus, a DNA tumor virus, expresses three viral oncoproteins (large, middle and small T antigens), causes malignant transformation in cell culture and induces multiple tumors in vivo. The middle T (MT) antigen seems to play an essential role in transformation and tumorigenicity. The observation that MT-overexpressing cell lines are able to grow in the absence of PDGF (platelet-derived growth factor) led...

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Source

Identifiers

PMID: 9181056

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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