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Article

Mechanisms of cell transformation induced by polyomavirus.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Jul 1999

Oliveira M L, Brochado S M, Sogayar M C

Abstract excerpt

Polyomavirus is a DNA tumor virus that induces a variety of tumors in mice. Its genome encodes three proteins, namely large T (LT), middle T (MT), and small T (ST) antigens, that have been implicated in cell transformation and tumorigenesis. LT is associated with cell immortalization, whereas MT plays an essential role in cell transformation by binding to and activating several cytoplasmic proteins that...

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Identifiers

PMID: 10454745
DOI: 10.1590/s0100-879x1999000700010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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