Article
Analysis of HLA-DPB1 polymorphisms in African-Americans with sarcoidosis.
American journal of respiratory and critical care medicine - 1 Jul 1998
Maliarik M J, Chen K M, Major M L, Sheffer R G, Popovich J, Rybicki B A, Iannuzzi M C
Abstract excerpt
Several studies have found weak associations between certain human leukocyte antigen (HLA) alleles and sarcoidosis, but none have been conclusive. Glutamic acid at position 69 in HLA-DPB1 has been reported to be strongly associated with chronic beryllium disease. The immunopathologic and clinical...
Topics
- Adult
- Aged
- Alleles
- Black People
- Female
- HLA-DP Antigens
- Humans
- Immunoglobulin Variable Region
- Male
- Middle Aged
- Phenotype
- Polymorphism, Genetic
- Sarcoidosis, Pulmonary
- Sequence Analysis, DNA
- Black or African American
