Article
Analysis of HLA-DPB1 polymorphisms in African-Americans with sarcoidosis.
American journal of respiratory and critical care medicine - 1 Jul 1998
Maliarik M J, Chen K M, Major M L, Sheffer R G, Popovich J, Rybicki B A, Iannuzzi M C
Abstract excerpt
Several studies have found weak associations between certain human leukocyte antigen (HLA) alleles and sarcoidosis, but none have been conclusive. Glutamic acid at position 69 in HLA-DPB1 has been reported to be strongly associated with chronic beryllium disease. The immunopathologic and clinical similarities between chronic beryllium disease (CBD) and sarcoidosis suggest that similar immune-response genes may be...
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