Article
BTNL2 allele associations with chronic beryllium disease in HLA-DPB1*Glu69-negative individuals.
Tissue antigens - 1 Dec 2007
Sato H, Spagnolo P, Silveira L, Welsh K I, du Bois R M, Newman L S, Maier L A
Abstract excerpt
Butyrophilin-like 2 (BTNL2) polymorphisms have been associated with sarcoidosis. We hypothesized that BTNL2 variants might confer a human leukocyte antigen (HLA)-independent risk for chronic beryllium disease (CBD), a granulomatous lung disease with similar clinical, radiological, and pathological features to sarcoidosis. Genomic DNA was obtained from CBD (n= 88), beryllium sensitized (BeS, n= 86), and beryllium...
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