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Article

Influence of MHC class II in susceptibility to beryllium sensitization and chronic beryllium disease.

Journal of immunology (Baltimore, Md. : 1950) - 15 Dec 2003

Maier Lisa A, McGrath Dierdre S, Sato Hiroe, Lympany Penny, Welsh Ken, Du Bois Roland, Silveira Lori, Fontenot Andrew P, Sawyer Richard T, Wilcox Eric, Newman Lee S

Abstract excerpt

A glutamic acid at residue 69(Glu(69)) in the HLA-DPB1 gene (Glu(69)) is associated with chronic beryllium disease (CBD) and possibly beryllium sensitization (BeS). This study tested the hypothesis that MHC class II polymorphisms are important in susceptibility to BeS and CBD and that the Glu(69) variant is related to markers of disease severity. Genomic DNA was obtained from BeS (n = 50), CBD (n = 104), and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14662898
DOI: 10.4049/jimmunol.171.12.6910

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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