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Article

HLA-DPB1 glutamate 69: a genetic marker of beryllium disease.

Science (New York, N.Y.) - 8 Oct 1993

Richeldi L, Sorrentino R, Saltini C

Abstract excerpt

Chronic beryllium disease (CBD) is a lung disorder related to beryllium exposure and is characterized by the accumulation in the lung of beryllium-specific CD4+ major histocompatibility complex (MHC) class II-restricted T lymphocytes. Evaluation of MHC class II genes in 33 CBD cases and 44 controls has shown a negative association with HLA-DPB1*0401 (P < 0.001) and a positive association with HLA-DPB1*0201 (P <...

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Source

Identifiers

PMID: 8105536
DOI: 10.1126/science.8105536

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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HLA-DPB1 glutamate 69: a genetic marker of beryllium disease.PMID 8105536Read ↗

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HLA-DP allele-specific T cell responses to beryllium account for DP-associated susceptibility to chronic beryllium disease.Semantic proximity Read ↗

HLA-DPB1 and chronic beryllium disease: a HuGE review.Semantic proximity Read ↗

Genetic susceptibility and immune-mediated destruction in beryllium-induced disease.Semantic proximity Read ↗

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The association between HLA-DPB1Glu69 and chronic beryllium disease and beryllium sensitization.Semantic proximity Read ↗

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