Article
The major histocompatibility complex gene region and sarcoidosis susceptibility in African Americans.
American journal of respiratory and critical care medicine - 1 Feb 2003
Rybicki Benjamin A, Maliarik Mary J, Poisson Laila M, Sheffer Roberta, Chen Kang Mei, Major Marcie, Chase Gary A, Iannuzzi Michael C
Abstract excerpt
Investigators have intensively evaluated the major histocompatibility (MHC) complex for sarcoidosis susceptibility genes with the majority of reports implicating the human leukocyte antigen (HLA)-DRB1 gene. Because most studies have been performed in white and Asian populations, we sought to determine which MHC genes might be risk factors for sarcoidosis in African Americans. We genotyped six microsatellite...
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