Article
Association of HLA-DRB1 with Sarcoidosis Susceptibility and Progression in African Americans.
American journal of respiratory cell and molecular biology - 1 Aug 2015
Levin Albert M, Adrianto Indra, Datta Indrani, Iannuzzi Michael C, Trudeau Sheri, Li Jia, Drake Wonder P, Montgomery Courtney G, Rybicki Benjamin A
Abstract excerpt
HLA-DRB1 is a sarcoidosis risk gene, and the *03:01 allele is strongly associated with disease resolution in European sarcoidosis cases. Whereas the HLA-DRB1 variation is associated with sarcoidosis susceptibility in African Americans, DRB1 risk alleles are not as well defined, and associations with disease resolution have not been studied. Associations between genotyped and imputed HLA-DRB1 alleles and disease...
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