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Article

Mutational analysis of the angiotensin II type 2 receptor: contribution of conserved extracellular amino acids.

Regulatory peptides - 31 Oct 1997

Heerding J N, Yee D K, Jacobs S L, Fluharty S J

Abstract excerpt

While much work has been done examining the ligand-binding characteristics of the AT1 receptor, very little attention has been focused on the AT2 receptor. Both receptors bind angiotensin II (AngII) with identical affinities, but share only 34% homology. Although it is tempting to assume that conserved residues between the two subtypes are responsible for the binding of AngII, there is little data to support this...

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Identifiers

PMID: 9652982
DOI: 10.1016/s0167-0115(97)01042-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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