Several interesting phenotypes of the AT1 receptor produced by site-directed mutagenesis.

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Article

Several interesting phenotypes of the AT1 receptor produced by site-directed mutagenesis.

Journal of the American Society of Nephrology : JASN - 1 Jan 1999

Conchon S, Miserey S, Parnot C, Monnot C, Corvol P, Clauser E

Abstract excerpt

The angiotensin II (AngII) AT1 receptor is a seven-transmembrane domain receptor coupled to a Gq/11 protein and phospholipase C, but also to other G proteins and to several tyrosine kinase pathways. These signaling pathways transduce inside the cells the classical actions of AngII (vasoconstricti...

Topics

Animals
GTP-Binding Proteins
Models, Molecular
Mutagenesis, Site-Directed
Mutation
Phenotype
Receptor, Angiotensin, Type 1
Receptor, Angiotensin, Type 2
Receptors, Adrenergic, beta
Receptors, Angiotensin
Signal Transduction

Source

Open in PubMed

Identifiers

PMID: 9892134

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9892134-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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