Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Participation of transmembrane proline 82 in angiotensin II AT1 receptor signal transduction.

Regulatory peptides - 5 Apr 2007

Reis Rosana I, Santos Edson L, Pesquero João B, Oliveira Laerte, Schanstra Joost P, Bascands Jean-Loup, Pecher Christiane, Paiva Antonio C M, Costa-Neto Claudio M

Abstract excerpt

Most of the classical physiological effects of the octapeptide angiotensin II (AngII) are produced by activating the AT1 receptor which belongs to the G-protein coupled receptor family (GPCR). Peptidic GPCRs may be functionally divided in three regions: (i) extracellular domains involved in ligan...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiotensin II
Share to Binding, Competitive
Share to Chlorocebus aethiops

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to COS Cells

Share to Proline

Share to Receptor, Angiotensin, Type 1

Share to Receptors, G-Protein-Coupled

Share to Structure-Activity Relationship

Source

Identifiers

PMID: 17239455
DOI: 10.1016/j.regpep.2006.11.028

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17239455-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Participation of transmembrane proline 82 in angiotensin II AT1 receptor signal transduction.PMID 17239455Read ↗

Angiotensin II AT1 receptor constitutive activation: from molecular mechanisms to pathophysiology.Semantic proximity Read ↗

Mutational analysis of the angiotensin II type 2 receptor: contribution of conserved extracellular amino acids.Semantic proximity Read ↗

Constitutive activity in the angiotensin II type 1 receptor: discovery and applications.Semantic proximity Read ↗

Several interesting phenotypes of the AT1 receptor produced by site-directed mutagenesis.Semantic proximity Read ↗

Tyr292 in the seventh transmembrane domain of the AT1A angiotensin II receptor is essential for its coupling to phospholipase C.Semantic proximity Read ↗

Molecular mechanisms of constitutive activity: mutations at position 111 of the angiotensin AT1 receptor.Semantic proximity Read ↗

[Structure and functions of the angiotensin II AT1 receptors during evolution].Semantic proximity Read ↗

Mutational analysis of the interaction of the N- and C-terminal ends of angiotensin II with the rat AT(1A) receptor.Semantic proximity Read ↗

Functional rescue of a defective angiotensin II AT1 receptor mutant by the Mas protooncogene.Semantic proximity Read ↗

Relationship between ligand binding and YIPP motif in the C-terminal region of human AT1 receptor.Semantic proximity Read ↗

Critical APJ receptor residues in extracellular domains that influence effector selectivity.Semantic proximity Read ↗

Structural basis for selectivity and diversity in angiotensin II receptors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.