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Article

Cisplatin resistance in cyclic AMP-dependent protein kinase mutants.

Pharmacology & therapeutics - 1 May 1998

Cvijic M E, Yang W L, Chin K V

Abstract excerpt

The emergence of cisplatin resistance poses a major problem to the successful treatment of a variety of human malignancies. Therefore, understanding the molecular mechanisms that underlie cisplatin resistance could significantly improve the clinical efficacy of this cytotoxic agent. Various studies have described that cellular sensitivity to cisplatin can be influenced by several signal transduction pathways. In...

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Identifiers

PMID: 9623882
DOI: 10.1016/s0163-7258(98)00002-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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