Article
[A study on the changes of DCC and MCC genes in colorectal carcinoma and adenoma].
Zhonghua nei ke za zhi - 1 Jul 1996
Zhou Y, Zhou D, Yuan A
Abstract excerpt
Both deleted in colorectal carcinoma (DCC) and mutated in colorectal carcinomas (MCC) genes are newly found tumour suppresser genes in colorectal carcinomas. In this study mutations of DCC gene and loss of heterozygosity (LOH) of MCC gene were detected with Southern blot and PCR methods respectively. The study consisted of 30 cases of colorectal adenoma (10 with mild, 10 with moderate and 10 with severe...
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