[Expression and loss of heterozygosity of DCC gene in human lung cancer].

Article

[Expression and loss of heterozygosity of DCC gene in human lung cancer].

Zhonghua yi xue za zhi - 1 Apr 1995

Zhang J, Ding F, Wang X

Abstract excerpt

The level of DCC mRNA expression was evaluated in tissue specimens from lung cancer patients by semiquantitative reverse transcription-polymerase chain reaction (RT-PCR) combined with Southern blot analysis. Obvious reduction of DCC gene expression was observed in 4 of 7 specimens (55%). In two s...

Topics

Adenocarcinoma
Alleles
Base Sequence
Carcinoma, Squamous Cell
Gene Deletion
Gene Expression
Genes, DCC
Heterozygote
Humans
Lung Neoplasms
Molecular Sequence Data
Polymerase Chain Reaction
RNA, Messenger

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