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Article

[Loss of heterozygosity involving DCC gene in human colorectal cancers is correlated with the metastatic potential].

Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 Jul 1996

Gao S, Xu W, Wan Y

Abstract excerpt

DCC gene located at chromosome 18q21.3 is an important tumor-supressor gene associated with tumorigenesis and progression, especially in colorectal carcinomas. Adopting Southern blot technique and RFLP analysis, 33 primary Chinese colorectal cancer patients were examined for loss of heterozygosity (LOH) of DCC gene. Among 16 informative cases, 6 (38%) showed allelic deletion. 18q LOH was correlated with lymph...

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Source

Identifiers

PMID: 9387312

Genes

DCC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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[Loss of heterozygosity involving DCC gene in human colorectal cancers is correlated with the metastatic potential].PMID 9387312Read ↗

[Structure and function of DCC (deleted in colorectal cancer) gene and its product].Semantic proximity Read ↗

[Expression and loss of heterozygosity of DCC gene in human lung cancer].Semantic proximity Read ↗

Frequent loss of expression without sequence mutations of the DCC gene in primary gastric cancer.Semantic proximity Read ↗

Analysis of the DCC tumor suppressor gene in testicular germ cell tumors: mutations and loss of expression.Semantic proximity Read ↗

[A study on the changes of DCC and MCC genes in colorectal carcinoma and adenoma].Semantic proximity Read ↗

Identification of a chromosome 18q gene that is altered in colorectal cancers.Semantic proximity Read ↗

Point mutations and allelic deletion of tumor suppressor gene DCC in human esophageal squamous cell carcinomas and their relation to metastasis.Semantic proximity Read ↗

Frequent allelic deletions and loss of expression characterize the DCC gene in male germ cell tumors.Semantic proximity Read ↗

The DCC gene: structural analysis and mutations in colorectal carcinomas.Semantic proximity Read ↗

Tumor suppressor genes involved in metastasis of lung and colorectal carcinomas.Semantic proximity Read ↗

Mutation and expression of the DCC gene in human lung cancer.Semantic proximity Read ↗

Concordant p53 and DCC alterations and allelic losses on chromosomes 13q and 14q associated with liver metastases of colorectal carcinoma.Semantic proximity Read ↗

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