Frequent loss of heterozygosity at the deleted in colorectal carcinoma gene locus and its association with histologic phenotypes in breast carcinoma.

doi:10.1007/BF00193166

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Article

Frequent loss of heterozygosity at the deleted in colorectal carcinoma gene locus and its association with histologic phenotypes in breast carcinoma.

Virchows Archiv : an international journal of pathology - 1 Jan 1995

Kashiwaba M, Tamura G, Ishida M

Abstract excerpt

Loss of heterozygosity (LOH) at the deleted in colorectal carcinoma gene (DCC), a tumour suppressor gene that encodes a protein with high homology to the neural cell adhesion molecule, was investigated in 42 surgical specimens of primary breast carcinoma. LOH was analysed in breast carcinoma by amplifying the DNA, spanning a variable number of tandem repeats site and a restriction fragment length polymorphism...

Topics

Alleles
Base Sequence
Biomarkers, Tumor
Breast Neoplasms
Carcinoma
Cell Separation
Colorectal Neoplasms
Gene Deletion
Gene Expression
Genes, DCC
Heterozygote

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Molecular Sequence Data

Phenotype

Polymerase Chain Reaction

Polymorphism, Restriction Fragment Length

Repetitive Sequences, Nucleic Acid

Source

Open in PubMed

Identifiers

PMID: 7633654
DOI: 10.1007/BF00193166

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7633654-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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