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Article

[Structure and function of DCC (deleted in colorectal cancer) gene and its product].

Nihon rinsho. Japanese journal of clinical medicine - 1 Apr 1996

Aoyama N, Minami R, Fujimori T, Maeda S

Abstract excerpt

The DCC gene is one of several genes altered during tumorigenesis. Recent studies demonstrate the existence of 29 exons and it spans 1.4 Mb. DCC gene is a candidate tumor-suppressor gene encoding a protein with a sequence similarity to cell adhesion molecule. Although the mutation of DCC gene was few, high incidence of LOH and decreased mRNA expression in colorectal cancer especially with hepatic metastasis was...

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Identifiers

PMID: 8920659

Genes

DCC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Structure and function of DCC (deleted in colorectal cancer) gene and its product].PMID 8920659Read ↗

The DCC gene: structural analysis and mutations in colorectal carcinomas.Semantic proximity Read ↗

[Loss of heterozygosity involving DCC gene in human colorectal cancers is correlated with the metastatic potential].Semantic proximity Read ↗

Genetic association of deleted in colorectal carcinoma variants with breast cancer risk: A case-control study.Semantic proximity Read ↗

Role of the Dependence Receptor DCC in Colorectal Cancer PathogenesisSemantic proximity Read ↗

Identification of a chromosome 18q gene that is altered in colorectal cancers.Semantic proximity Read ↗

[A study on the changes of DCC and MCC genes in colorectal carcinoma and adenoma].Semantic proximity Read ↗

[Expression and loss of heterozygosity of DCC gene in human lung cancer].Semantic proximity Read ↗

The DCC Protein and Prognosis in Colorectal CancerSemantic proximity Read ↗

Point mutations and allelic deletion of tumor suppressor gene DCC in human esophageal squamous cell carcinomas and their relation to metastasis.Semantic proximity Read ↗

Analysis of the DCC tumor suppressor gene in testicular germ cell tumors: mutations and loss of expression.Semantic proximity Read ↗

Frequent loss of heterozygosity at the deleted in colorectal carcinoma gene locus and its association with histologic phenotypes in breast carcinoma.Semantic proximity Read ↗

DCC expression is altered by multiple mechanisms in brain tumours.Semantic proximity Read ↗

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