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Article

Evaluation of genetic mutations of tumor suppresser genes in colorectal cancer patients.

Hepato-gastroenterology - 1 Jan 2000

Kubo Hiroyuki, Miki Chikao, Kusunoki Masato

Abstract excerpt

BACKGROUND/AIMS: The mutation of tumor suppresser genes of colorectal cancer was evaluated to clarify its significance in the clinical management of colorectal cancer patients. METHODOLOGY: Polymerase chain reaction amplification was performed to investigate the loss of heterozygosity (LOH) of the DCC (deleted-in-colorectal-carcinoma) gene and p53 gene in 76 colorectal cancers. RESULTS: Thirty-five of 76 tumors...

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Source

Identifiers

PMID: 15011843

Genes

DCC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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