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Article

Early loss of deleted in colorectal carcinoma gene transcript detected in a group of benign colon adenomas.

Journal of biomedical science - 1 Jan 2000

Traicoff J une L, Willson James K V, Markowitz Sanford D

Abstract excerpt

We examined the expression of the putative tumor suppressor gene deleted in colorectal carcinoma (DCC) in human colon adenoma tissues and cell lines. One allele of DCC is deleted in 70% of human colon carcinomas, and DCC expression is undetectable in 90% of colon carcinoma cell lines. One DCC allele is also deleted in 50% of human colon adenomas, but results from protein expression studies have differed as to...

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Source

Identifiers

PMID: 12432238
DOI: 10.1159/000067291

Genes

DCC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Early loss of deleted in colorectal carcinoma gene transcript detected in a group of benign colon adenomas.PMID 12432238Read ↗

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