[Genetic alterations of human colorectal cancer].

Article

[Genetic alterations of human colorectal cancer].

Gan to kagaku ryoho. Cancer & chemotherapy - 1 Feb 1994

Suzuki T, Ishioka C, Gamo M, Niitani T, Shimodaira H, Kanbe M, Yamazaki T, Yusa Y, Kanamaru R

Abstract excerpt

Genetic alterations of several oncogenes and tumor suppressor genes are associated with human colorectal carcinogenesis. Especially in mutations, the K-ras, p53, APC and DCC gene frequently occurred, and these gene alterations seem to have important roles in colorectal carcinogenesis. We investig...

Topics

Colonic Neoplasms
Colorectal Neoplasms
Genes, APC
Genes, DCC
Genes, Tumor Suppressor
Genes, p53
Genes, ras
Humans
Mutation
Polymerase Chain Reaction
Tumor Cells, Cultured

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