Article
Spectra of spontaneous frameshift mutations at the hisD3052 allele of Salmonella typhimurium in four DNA repair backgrounds.
Genetics - 1 May 1998
DeMarini D M, Shelton M L, Abu-Shakra A, Szakmary A, Levine J G
Abstract excerpt
To characterize the hisD3052 -1 frameshift allele of Salmonella typhimurium, we analyzed approximately 6000 spontaneous revertants (rev) for a 2-base deletion hotspot within the sequence (CG)4, and we sequenced approximately 500 nonhotspot rev. The reversion target is a minimum of 76 bases (nucle...
Topics
- Alcohol Oxidoreductases
- Alleles
- Bacterial Proteins
- Base Sequence
- DNA Fingerprinting
- DNA Helicases
- DNA Mutational Analysis
- DNA Repair
- DNA, Bacterial
- Escherichia coli Proteins
- Frameshift Mutation
- Molecular Sequence Data
- Mutagenicity Tests
- Nucleic Acid Conformation
- Salmonella typhimurium
- Sequence Deletion