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Article

Sequence analysis of mutations arising during prolonged starvation of Salmonella typhimurium.

Genetics - 1 Oct 1992

Prival M J, Cebula T A

Abstract excerpt

We have examined the effects of prolonged histidine deprivation on the reversion of Salmonella typhimurium histidine auxotrophs containing either hisG46, a missense mutation (CTC----CCC), or hisG428, an ochre mutation (CAA----TAA). Both of these mutants can revert to His+ via intragenic and extragenic mechanisms. Whereas the hisG46 mutant site consists of G/C base pairs, extragenic suppression of hisG46 requires...

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Identifiers

PMID: 1427030
DOI: 10.1093/genetics/132.2.303
PMCID: PMC1205137

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