Article
Mutagenicity and mutation spectra of 2-acetylaminofluorene at frameshift and base-substitution alleles in four DNA repair backgrounds of Salmonella.
Mutation research - 1 Mar 1995
Shelton M L, DeMarini D M
Abstract excerpt
We used colony probe hybridization procedures to determine the mutations in approximately 600 revertants of the -1 frameshift allele hisD3052 and approximately 200 revertants of the base-substitution allele hisG46 of Salmonella typhimurium induced by 2-acetylaminofluorene (2-AAF) in the presence...
Topics
- 2-Acetylaminofluorene
- Alleles
- Animals
- Aroclors
- Base Sequence
- DNA
- DNA Adducts
- DNA Repair
- DNA, Bacterial
- Dose-Response Relationship, Drug
- Frameshift Mutation
- Guanosine Diphosphate
- Male
- Microsomes, Liver
- Models, Genetic
- Molecular Sequence Data
- Mutagenesis
- Mutagenicity Tests