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Article

Influence of DNA repair on mutation spectra in Salmonella.

Mutation research - 30 May 2000

DeMarini D M

Abstract excerpt

This paper reviews the influence of DNA repair on spontaneous and mutagen-induced mutation spectra at the base-substitution (hisG46) and -1 frameshift (hisD3052) alleles present in strains of the Salmonella (Ames) mutagenicity assay. At the frameshift allele (mostly a CGCGCGCG target), DeltauvrB influences the frequency of spontaneous hotspot mutations (-CG), duplications, and deletions, and it also shifts the...

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Identifiers

PMID: 10838131
DOI: 10.1016/s0027-5107(00)00013-0

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