Article
The DeltauvrB mutations in the Ames strains of Salmonella span 15 to 119 genes.
Mutation research - 1 Nov 2001
Porwollik S, Wong R M, Sims S H, Schaaper R M, DeMarini D M, McClelland M
Abstract excerpt
The DeltauvrB mutations present in strains of Salmonella enterica Typhimurium used commonly in the Salmonella (Ames) mutagenicity assay were isolated independently for at least five different his mutants. These deletions all involved the galactose operon, biotin operon, nucleotide-excision-repair uvrB gene, and chlorate-resistance genes. Beyond this, the size of the deletions and the number and type of genes...
Topics
- DNA Helicases
- DNA Repair
- Escherichia coli Proteins
- Gene Deletion
- Genes, Bacterial
- Multigene Family
- Mutation
- Oligonucleotide Array Sequence Analysis
- Salmonella typhimurium
- Species Specificity