Mutational spectrum of revertants in the hisD3052 allele of Salmonella typhimurium induced by hydrogen peroxide-activated benzidine.

doi:10.1016/0027-5107(94)90068-x

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Article

Mutational spectrum of revertants in the hisD3052 allele of Salmonella typhimurium induced by hydrogen peroxide-activated benzidine.

Mutation research - 1 Nov 1994

Wallace R E, Josephy P D

Abstract excerpt

Benzidine is mutagenic in a modified Ames (Salmonella typhimurium) assay, which uses hydrogen peroxide-dependent peroxidative activation. The mutational specificity of benzidine was investigated in tester strain TA98, which reverts by frameshifts of the hisD3052 allele. The most frequently observ...

Topics

Alcohol Oxidoreductases
Alleles
Base Sequence
Benzidines
DNA Primers
Genes, Bacterial
Histidine
Hydrogen Peroxide
Molecular Sequence Data
Mutagenicity Tests
Mutation
Salmonella typhimurium

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