Article
Mutation spectra of Glu-P-1 in Salmonella: induction of hotspot frameshifts and site-specific base substitutions.
Environmental and molecular mutagenesis - 1 Jan 1994
Levine J G, Knasmüller S, Shelton M L, DeMarini D M
Abstract excerpt
We used colony probe hybridization and PCR/DNA sequence analysis to determine the mutations in approximately 1,640 revertants of the -1 frameshift allele hisD3052 and approximately 260 revertants of the base substitution allele hisG46 of Salmonella typhimurium induced by the heterocyclic amine co...
Topics
- Alleles
- Aminobiphenyl Compounds
- Animals
- Base Sequence
- DNA Repair
- DNA, Bacterial
- Dose-Response Relationship, Drug
- Frameshift Mutation
- Imidazoles
- Molecular Sequence Data
- Mutagenicity Tests
- Mutagens